Fresh analysis reveals that individuals who stop using popular slimming jabs like Mounjaro or Wegovy may regain lost weight far faster than those who stop traditional diet and exercise programs.
Published data in a leading medical journal points out that while overweight individuals often shed a large proportion of their body weight while using the jabs, the weight is regained at an average rate of 0.8 kg per month once they quit.
"Individuals purchasing these medications must be cognizant of the potential of fast weight regain when the treatment is stopped," cautioned researcher Dr. Susan Jebb.
That rate of regain suggests a return to original weight within about 18 months.
Comparing Approaches
The study, which looked at 37 of trials involving thousands of patients, compared the results of the injectable medications with older methods.
Scientists point out that people who shed pounds through diet and exercise generally see a less rapid weight regain—approximately 100 grams monthly—post-intervention.
Explaining the Fast Rebound
Nutrition scientists suggest the mechanism of the drugs explains the accelerated weight return.
GLP-1 drugs mimic a body's own chemical called glucagon-like peptide-1, which controls hunger.
"Artificially providing GLP-1 concentrations far above than normal might result in the body to produce less of its endogenous GLP-1, and may also lessen sensitivity to its actions," said Dr. Adam Collins, a nutrition researcher.
"Stopping of this GLP-1 'fix' means hunger is uncontrolled, making overeating a significant risk."
A Chronic Condition?
Medical guidelines suggest the jabs for individuals with weight-linked medical conditions, accompanied by prescribed diet and exercise modifications.
Professionals say that, given the likelihood of relapse, the therapy might need to be long-term.
This opinion is echoed by pharmaceutical companies, who note that the results "underscore the chronic character of obesity," comparing it to managing conditions like high blood pressure.
User Accounts
Users who have stopped the medication report a powerful resurgence of appetite.
"It felt as if a switch activating and I was suddenly ravenous," described an individual.
This difficulty is exacerbated if users have not developed permanent dietary or behavioural changes during treatment.
Significant Adoption
Figures suggest that millions of people in the UK have tried weight-loss jabs in the past year, with desire remaining high.
- Adoption is greater among women compared to men.
- The middle-aged age group shows the highest usage rates.
- Many obtain the medications through private prescriptions rather than the NHS.
In conclusion, experts emphasize that while the jabs are effective agents for weight loss, they are not a permanent fix and lasting health benefits hinges on ongoing lifestyle management.
